Figure 4.

Heatmap displaying the expression level of genes related to cholesterol synthesis (a) and chemokine signaling (b) in VAT of the 3 groups of mice. Samples from Ref, HFoleic, and HFepa groups are illustrated with green circles, red circles and blue squares, respectively. Heatmap were generated using the correlation-based distance calculation and the ward method as clustering criteria. The magnitude of expression level is represented from white (low) to clear blue (intermediate) and dark blue (high). HFoleic, mice from oleic/control lineage fed with the obesogenic diet; HFepa, mice from EPA/omega 3 lineage fed with the obesogenic diet; Ref, mice from oleic/control lineage fed with the normocaloric diet.