Figure 1.

Timeline of study showing gestation and lactation periods. Injected and oral vaccines were administered to sows during gestation: INJ (injection of PEDV vaccine), LOV (low-dose oral PEDV vaccine), HOV (high-dose oral PEDV vaccine), CON (non-vaccinated controls). ¹ Milk was collected on day 6 post-challenge. ² Piglets were challenged with PEDV virus between days 3–5 of lactation. ³ Piglets were observed for signs of diarrhea, dehydration, and overall health for 11 d post-challenge. ⁴ Animals were euthanized on day 11 post-challenge.