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Activation of lymphoid cells after oral-SLGN treatment in CHB subjects. Gating strategy and cell surface expression of CD69 on (A) MAIT, (B) CD8+ T and (C) CD56+ NK cells. Comparative analyses of frequencies of CD69 on (D) MAIT, (E) CD8+ T and (F) CD56+ NK from baseline and 8 h samples in SLGN-treated (3.0 mg dose, n = 14) CHB patients. Significance was calculated by a two-tailed paired Student’s t test, and p value ≤ 0.05 * and 0.01 ** show grades of significance.
