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. 2021 Dec 7;9(12):1447. doi: 10.3390/vaccines9121447

Table 5.

VE against any influenza stratified by prior vaccination.

Current Vaccination Dose n (%) Crude VE
(95% CI)
Adjusted VE
(95% CI) a
Adjusted VE
(95% CI) b
Unvaccinated in prior season Cases (n = 544) Controls (n = 762)
0 458 (84) 493 (65) Reference Reference Reference
1 25 (5) 45 (6) 40% (1% to 64%) 44% (−22% to 74%) 40% (−35% to 73%)
2 61 (11) 224 (29) 71% (60% to 79%) 64% (42% to 78%) 60% (34% to 75%)
Vaccinated in prior season Cases (n = 255) Controls (n = 434)
0 55 (22) 68 (16) Reference Reference Reference
1 52 (20) 94 (22) 32% (−12% to 58%) 76% (31% to 91%) 80% (36% to 94%)
2 148 (58) 272 (62) 33% (−1% to 55%) 69% (29% to 87%) 75% (36% to 90%)

VE; vaccine effectiveness. CI; confidence interval. a Stratified variables: enrolment season, clinic, week, and age (1-year interval). b Stratified variables: enrolment season, clinic, week, and age (1-year interval). Adjusted variables: sex, sibling, nursery school, interval between illness onset and enrolment (0–2/≥3 days), medical comorbidities, number of outpatient visits (0–4/5–9/≥10) in the prior season, influenza diagnosis in the prior season, and influenza vaccination until the season before prior season (0/≥1).