Table 7.
T1/2 | Tmax | Cmax | AUC0_Tlast | AUCINF | %F a | |
---|---|---|---|---|---|---|
(h) | (h) | (µg/mL) | (h × µg/mL) | (h × µg/mL) | ||
Day 1 | ||||||
Male | 18.52 | 1.00 | 2.62 | 63.96 | 88.78 | 8.12 |
Female | 13.45 | 8.00 | 4.79 | 105.68 | 129.75 | 13.89 |
Day 14 | ||||||
Male | 10.68 | 2.00 | 4.58 | 61.22 | 64.79 | 5.07 |
Female | 9.01 | 4.00 | 4.39 | 77.19 | 80.30 | 7.45 |
a-%F was calculated by the following equation: .