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. 2021 Dec 17;13(12):2186. doi: 10.3390/pharmaceutics13122186

Table 7.

Pharmacokinetic parameters following IM administration of 2.6 mg Nano-mupirocin per rat.

T1/2 Tmax Cmax AUC0_Tlast AUCINF %F a
(h) (h) (µg/mL) (h × µg/mL) (h × µg/mL)
Day 1
Male 18.52 1.00 2.62 63.96 88.78 8.12
Female 13.45 8.00 4.79 105.68 129.75 13.89
Day 14
Male 10.68 2.00 4.58 61.22 64.79 5.07
Female 9.01 4.00 4.39 77.19 80.30 7.45

a-%F was calculated by the following equation: % F=AUC 0_Tlast after IM administrationAUC 0_Tlast after IV 10 mg/kg administration×100.