Table 1.

Inhibitory effects of ent-cis-195A and cis-211A on [³H]nicotine uptake by TR-BBB13 cells and [³H]verapamil uptake by TR-iBRB2 cells.

Conditions	Percentage of Control
	[3H]Nicotine Uptake	[3H]Verapamil Uptake
Control	100 ± 5	100 ± 4
ent-cis-195A	31.6 ± 1.7 *	66.9 ± 2.5 *
cis-211A	60.0 ± 3.5 *	70.6 ± 4.1 *

[³H]Nicotine uptake (0.1 μCi/well, 6.0 nM) by TR-BBB13 cells was measured at 37 °C for 10 sec in the absence (control) or presence of test compounds at 200 µM with 1.0% dimethyl sulfoxide (DMSO). Similarly, [³H]verapamil uptake by TR-iBRB2 cells was performed at 37 °C for 3 min. Each value represents the mean ± standard error of the mean S.E.M. (n = 3–6). *p < 0.01, significantly different from the control in Dunnett’s test.