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. 2021 Dec 16;2(4):618–653. doi: 10.1002/mco2.104

FIGURE 4.

FIGURE 4

NF‐κB pathway modulates tumor microenvironment. The NF‐κB signaling pathway is tightly correlated to the various components of the tumor microenvironment. NF‐κB can not only drive the expression of chemokines in stromal cells, tumor cells, and immune cells in the tumor microenvironment but can also be activated in each cell to transcriptionally enhance the expression of cytokines and promote tumor proliferation and metastasis