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Gene regulation in tumor and spleen tissues from treated mice. (A) Pdl1, Calreticulin, Hmgb1, Cd3e, Cd4, and Cd8a expressions were determined by RT-qPCR in tumor tissues collected from C57BL/6N mice, and (B) Pdl1, Foxp3, Ifng, Cd3e, and Cd8a expressions were determined in spleen tissues collected from the mice within the same study. Data are presented as means ± SEM (n = 3). One-way ANOVA: * p < 0.05, ** p < 0.01, *** p < 0.001.
