Table 1.

Demographics of patient records.

	All-Cause Pneumonia (n = 70,402)	Pneumonia (n = 61,559)		Meningitis (n = 192)		Bacteremia (n = 8587)		Otitis Media (n = 11,061)	Other Invasive Diseases * (n = 7463)	Total (n = 91,654)
		Pneumococcal (n = 967)	Unspecified (n = 60,592)	Pneumococcal (n = 129)	Unspecified (n = 63)	Pneumococcal (n = 121)	Unspecified (n = 8466)
Male, n; % [95% CI]	37,830; 53.73 [53.37–54.10]	513; 53.05 [49.90–56.19]	32,380; 53.43 [53.04–53.83]	63; 48.83 [40.21–57.46]	27; 42.85 [30.63–55.07]	65; 53.71 [44.83–62.60]	4440; 52.44 [51.38–53.50]	5640; 50.98 [50.05–51.92]	5640; 75.57 [74.6–76.55]	49,168; 53.65 [53.32–53.97]
Mean age (SD)	72.8 (18.76)	73.20 (16.63)	75.23 (16.83)	62.55 (14.89)	63.29 (17.82)	70.53 (16.06)	75.69 (14.72)	46.58 (18.39)	66.26 (15.92)	69.56 (20.28)
Age group, n; % [95% CI]
15–64 years	18,077; 25.68 [25.35–26.00]	272; 28.13 [25.29–30.96]	13,284; 21.92 [21.59–22.25]	63; 48.84 [40.21–57.46]	26; 41.27 [29.11–53.43]	50; 41.32 [32.55–50.10]	1709; 20.19 [19.33–21.04]	9077; 82.06 [81.35–82.78]	2202; 29.51 [28.47–30.54]	29,940; 32.67 [32.36–32.97]
≥65 years	52,325; 74.32 [74.00–74.65]	695; 71.87 [69.04–74.71]	47,308; 78.08 [77.75–78.41]	66; 51.16 [42.54–59.79]	37; 58.73 [46.57–70.89]	71; 58.68 [49.90–67.45]	6757; 79.81 [78.96–80.67]	1984; 17.94 [17.22–18.65]	5261; 70.49 [69.46–71.53]	61,714; 67.33 [67.03–67.64]
Any comorbidity n; % [95%CI]	56,705; 80.54 [80.25–80.84]	786; 81.28 [78.82–83.74]	49,872; 82.31 [82.00–82.61]	87; 67.44 [59.36–75.53]	47; 74.60 [63.85–85.35]	93; 76.86 [69.35–84.37]	7614; 89.94 [89.30–90.58]	3168; 28.64 [27.80–29.48]	6215; 83.28 [82.43–84.12]	68,765; 75.03 [74.75–75.31]
Chronic renal failure	11,386; 16.17 [15.90–16.44]	130; 13.44 [11.29–15.59]	10,508; 17.34 [17.04–17.64]	6; 4.65 [1.02–8.29]	6; 9.52 [2.28–16.77]	14; 11.57 [5.87–17.27]	2028; 23.95 [23.05–24.86]	122; 1.10 [0.91–1.30]	1322; 17.71 [16.85–18.58]	13,760; 15.01 [14.78–15.24]
Cardiovascular disease	38,109; 54.13 [53.76–54.50]	469; 48.50 [45.35–51.65]	34,603; 57.11 [56.71–57.50]	36; 27.91 [20.17–35.65]	23; 36.51 [24.62–48.40]	45; 37.19 [28.58–45.80]	5079; 59.99 [58.95–61.04]	703; 6.36 [5.90–6.81]	4359; 58.41 [57.29–59.53]	44,752; 48.83 [48.5–49.15]
Respiratory disease	19,734; 28.03 [27.70–28.36]	255; 26.37 [23.59–29.15]	16,599; 27.39 [27.04–27.75]	10; 7.75 [3.14–12.37]	4; 6.35 [0.33–12.37]	19; 15.70 [9.22–22.19]	1441; 17.02 [16.22–17.82]	510; 4.61 [4.22–5.00]	1460; 19.56 [18.66–20.46]	21,738; 23.72 [23.44–23.99]
Diabetes	13,408; 19.04 [18.75–19.33]	184; 19.03 [16.55–21.50]	11,686; 19.29 [18.97–19.60]	16; 12.40 [6.71–18.09]	6; 9.52 [2.28–16.77]	15; 12.40 [6.52–18.27]	2040; 24.09 [23.19–25.01]	531; 4.80 [4.40–5.20]	1647; 22.07 [21.13–23.01]	16,516; 18.02 [17.77–18.27]
Neoplasia	13,759; 19.54 [19.25–19.84]	204; 21.10 [18.52–23.67]	12,096; 19.96 [19.64–20.28]	20; 15.50 [9.26–21.75]	13; 20.63 [10.64–30.63]	28; 23.14 [15.63–30.65]	2739; 32.35 [31.36–33.35]	538; 4.86 [4.46–5.26]	1433; 19.2 [18.31–20.1]	17,195; 18.76 [18.51–19.01]
Others	25,517; 36.24 [35.89–36.60]	370; 38.26 [35.20–41.33]	22,611; 37.32 [36.93–37.70]	31; 24.03 [16.66–31.40]	16; 25.40 [14.65–36.15]	39; 32.23 [23.90–40.56]	3770; 44.53 [43.47–45.59]	1029; 9.30 [8.76–9.84]	2429; 32.55 [31.48–33.61]	30,595; 33.38 [33.08–33.69]

* At least one of (ICD-9-CM code): Infective pericarditis (420.9), acute and subacute endocarditis (421.1–421.9), empyema (510.9), pneumococcal peritonitis (567.1), spontaneous bacterial peritonitis (567.23), pyogenic arthritis (711.0/711.9), acute osteomyelitis (730.0x–730.2x), pleural effusion with unspecified bacterial cause (511.1), AOM complication with miryngotomy/tympanostomy with drainage of middle ear (20.0). AOM: acute otitis media; CI: confidence interval; ICD-9-CM: International Classification of Diseases, Ninth Revision, Clinical Modification; SD, standard deviation.