Figure 2.

(A) Human plasma kininogen showing alternative splicing products of KNG1 gene messenger RNA–HK and LK. Both forms of protein have similar D1, D2, D3, and D4 domains, but different D5 domains. Domain 6 is absent in LK and the molecular weight of this form is lower than that of HK. (B) Human HK amino acid sequence according to UniProt P01042 with the indication of domains. N-terminus and C-terminus marked by corresponding letters. Disulfide (SS) bonds between the respective domains are marked.