Table 3.
Study arms and respective disintegration sites.
| Combination | Esophagus | Stomach | Duodenum | Jejunum | Ileum |
|---|---|---|---|---|---|
| Vcaps® HPMC capsule |
2 | 2 | 1 | 1 | - |
| Vcaps® Plus HPMC capsule | - | 5 | - | 1 | - |
| DRcaps® designed release capsule |
1 | 1 | - | 4 | - |
| Vcaps® HPMC capsule within Vcaps® HPMC capsule (VC-in-VC) |
1 | 3 | - | 2 | - |
| Vcaps® Plus HPMC capsule within Vcaps® HPMC capsule (VCP-in-VC) |
- | 4 | - | 2 | - |
| DRcaps® designed release capsule within Vcaps® HPMC capsule (DR-in-VC) |
1 | 1 | 1 | 1 | 2 |
| DRcaps® designed release capsule within gelatin capsule (DR-in-HGC) |
- | 4 | - | 1 | 1 |
| Vcaps® HPMC capsule within DRcaps® designed release capsule (VC-in-DR) | - | 1 | - | 4 | 1 |
| Vcaps® Plus HPMC capsule within DRcaps® designed release capsule (VCP-in-DR) |
- | 1 | - | 3 | 2 |
| DRcaps® designed release capsule within DRcaps® designed release capsule (DR-in-DR) |
- | - | - | - | 6 |