Table 4.
Lipid Profile | Study Characteristics | Effect (Change) | ||||||
---|---|---|---|---|---|---|---|---|
Type of Population | Source of (poly)phenols /Type of (poly)phenols | Doses (mg/day) |
Duration (days) | Variability of the Results (CV%) | Effect Size Range | Consistency of the Change 1 | Consistency of the Statistical Significance 2 | |
T-C (mg/dL) (n = 15) [25,27,28,32,34,35,36,37,38,39,40,41,42,44,45] |
Mix (healthy, osteopenia, dyslipidaemia) | Snack bar (soy protein, mix isoflavones), dried apple (proanthocyanins, hydroxycinnamic and anthocyanins), dried prunes (chlorogenic, neochlorogenic acids), chocolate 99% (procyanidins, epicatechins, quercetin glycosides), red wine and dealcoholized red wine (anthocyanins and resveratrol), beer and dealcoholized beer (prenylflavonoids) and mix (poly)phenols (isoflavones, daidzein, genistein, procyanidin, flavones, resveratrol, anthocyanins, quercetin, myricetin, kaempferol) | ~43–1000 | 14–365 | ~10–48 | (−22.0, +11.6) | No | No |
LDL-C (mg/dL) (n = 15) [25,27,28,32,34,35,36,37,38,39,40,41,42,44,45] |
Mix (healthy, osteopenia, dyslipidaemia) | Snack bar (soy protein, mix isoflavones), dried apple (proanthocyanins, hydroxycinnamic and anthocyanins), dried prunes (chlorogenic, neochlorogenic acids), chocolate 99% (procyanidins, epicatechins, quercetin glycosides), red wine and dealcoholized red wine (anthocyanins and resveratrol), beer and dealcoholized beer (prenylflavonoids) and mix (poly)phenols (isoflavones, daidzein, genistein, procyanidin, flavones, resveratrol, anthocyanins, quercetin, myricetin, kaempferol) | ~43–1000 | 14–365 | ~13–92 | (−23.9, +18.1) | No | No |
HDL-C (mg/dL) (n = 16) [25,27,28,31,32,34,35,36,37,38,39,40,41,42,44,45] |
Mix (healthy, osteopenia, dyslipidaemia, metabolic syndrom) | Snack bar (soy protein, mix isoflavones), dried apple (proanthocyanins, hydroxycinnamic and anthocyanins), dried prunes (chlorogenic, neochlorogenic acids), chocolate 99% (procyanidins, epicatechins, quercetin glycosides), red wine and dealcoholized red wine (anthocyanins and resveratrol), beer and dealcoholized beer (prenylflavonoids) and mix (poly)phenols (isoflavones, daidzein, genistein, procyanidin, flavones, resveratrol, anthocyanins, quercetin, myricetin, kaempferol) | ~43–1000 | 14–365 | ~10–66 | (−11.9, +11.1) | No | No |
TGs (mg/dL) (n = 16) [25,27,28,31,32,34,35,36,37,38,39,40,41,42,44,45] |
Mix (healthy, osteopenia, dyslipidaemia, metabolic syndrom) | Snack bar (soy protein, mix isoflavones), dried apple (proanthocyanidins, hydroxycinnamics and anthocyanins), dried prunes (chlorogenic, neochlorogenic acids), chocolate 99% (procyanidins, epicatechins, quercetin glycosides), red wine and dealcoholized red wine (anthocyanins and resveratrol), beer and dealcoholized beer (prenylflavonoids) | ~43–1000 | 14–365 | ~10–80 | (−23.0 +13.0) | No | No |
and mix (poly)phenols (isoflavones, daidzein, genistein, procyanidin, flavones, resveratrol, anthocyanins, quercetin, myricetin, kaempferol) |
n, number of studies examined; T-C, total cholesterol; LDL-C, low-density lipoprotein-cholesterol; HDL-C, high-density lipoprotein-cholesterol; TGs, triglycerides; CV%, calculated for the reported results in the different groups examined. 1: Yes = all results in the same direction; No = results indicate increase and decrease; 2: Yes = all results reported to be significant (S) or not-significant (NS); No = some results are significant some are not.