Table 4.
Summary of the collected responses of the lipid biomarkers to the daily consumption of mix (poly)phenols of different sources in postmenopausal women (for specific results in each study please refer to Tables S4–S7).
Lipid Profile | Study Characteristics | Effect (Change) | ||||||
---|---|---|---|---|---|---|---|---|
Type of Population | Source of (poly)phenols /Type of (poly)phenols | Doses (mg/day) |
Duration (days) | Variability of the Results (CV%) | Effect Size Range | Consistency of the Change 1 | Consistency of the Statistical Significance 2 | |
T-C (mg/dL) (n = 15) [25,27,28,32,34,35,36,37,38,39,40,41,42,44,45] |
Mix (healthy, osteopenia, dyslipidaemia) | Snack bar (soy protein, mix isoflavones), dried apple (proanthocyanins, hydroxycinnamic and anthocyanins), dried prunes (chlorogenic, neochlorogenic acids), chocolate 99% (procyanidins, epicatechins, quercetin glycosides), red wine and dealcoholized red wine (anthocyanins and resveratrol), beer and dealcoholized beer (prenylflavonoids) and mix (poly)phenols (isoflavones, daidzein, genistein, procyanidin, flavones, resveratrol, anthocyanins, quercetin, myricetin, kaempferol) | ~43–1000 | 14–365 | ~10–48 | (−22.0, +11.6) | No | No |
LDL-C (mg/dL) (n = 15) [25,27,28,32,34,35,36,37,38,39,40,41,42,44,45] |
Mix (healthy, osteopenia, dyslipidaemia) | Snack bar (soy protein, mix isoflavones), dried apple (proanthocyanins, hydroxycinnamic and anthocyanins), dried prunes (chlorogenic, neochlorogenic acids), chocolate 99% (procyanidins, epicatechins, quercetin glycosides), red wine and dealcoholized red wine (anthocyanins and resveratrol), beer and dealcoholized beer (prenylflavonoids) and mix (poly)phenols (isoflavones, daidzein, genistein, procyanidin, flavones, resveratrol, anthocyanins, quercetin, myricetin, kaempferol) | ~43–1000 | 14–365 | ~13–92 | (−23.9, +18.1) | No | No |
HDL-C (mg/dL) (n = 16) [25,27,28,31,32,34,35,36,37,38,39,40,41,42,44,45] |
Mix (healthy, osteopenia, dyslipidaemia, metabolic syndrom) | Snack bar (soy protein, mix isoflavones), dried apple (proanthocyanins, hydroxycinnamic and anthocyanins), dried prunes (chlorogenic, neochlorogenic acids), chocolate 99% (procyanidins, epicatechins, quercetin glycosides), red wine and dealcoholized red wine (anthocyanins and resveratrol), beer and dealcoholized beer (prenylflavonoids) and mix (poly)phenols (isoflavones, daidzein, genistein, procyanidin, flavones, resveratrol, anthocyanins, quercetin, myricetin, kaempferol) | ~43–1000 | 14–365 | ~10–66 | (−11.9, +11.1) | No | No |
TGs (mg/dL) (n = 16) [25,27,28,31,32,34,35,36,37,38,39,40,41,42,44,45] |
Mix (healthy, osteopenia, dyslipidaemia, metabolic syndrom) | Snack bar (soy protein, mix isoflavones), dried apple (proanthocyanidins, hydroxycinnamics and anthocyanins), dried prunes (chlorogenic, neochlorogenic acids), chocolate 99% (procyanidins, epicatechins, quercetin glycosides), red wine and dealcoholized red wine (anthocyanins and resveratrol), beer and dealcoholized beer (prenylflavonoids) | ~43–1000 | 14–365 | ~10–80 | (−23.0 +13.0) | No | No |
and mix (poly)phenols (isoflavones, daidzein, genistein, procyanidin, flavones, resveratrol, anthocyanins, quercetin, myricetin, kaempferol) |
n, number of studies examined; T-C, total cholesterol; LDL-C, low-density lipoprotein-cholesterol; HDL-C, high-density lipoprotein-cholesterol; TGs, triglycerides; CV%, calculated for the reported results in the different groups examined. 1: Yes = all results in the same direction; No = results indicate increase and decrease; 2: Yes = all results reported to be significant (S) or not-significant (NS); No = some results are significant some are not.