Table 2.
Comorbidities, Malnutrition-Inflammation Score and Subjective Global Assessment Score in different age groups of CKD stage 3–5 patients.
| Age Groups | ||||||
|---|---|---|---|---|---|---|
| <60 | 60–69 | 70–79 | 80–89 | ≥90 | p-Values | |
| N (all: 436) | 62 | 74 | 106 | 140 | 54 | |
| Males/females | 35/27 | 51/23 | 75/31 | 79/61 | 18/36 | <0.001 |
| CCI, median (IQR) | 5 (3) | 7 (4) | 8 (2) | 8 (3) | 8 (1) | <0.001 |
| MIS, median (IQR) | 4 (4) | 5 (4) | 5 (4) | 5 (3) | 7 (4) | <0.001 |
| SGA, n (%) | <0.001 | |||||
| A | 57 (91.9%) | 61 (82.4%) | 94 (88.7%) | 105 (75.5%) | 23 (42.6%) | |
| B | 3 (4.8%) | 12 (16.2%) | 11 (10.4%) | 31 (22.3%) | 29 (53.7%) | |
| C | 1 (1.6%) | 1 (1.4%) | 1 (0.9%) | 3 (2.2%) | 2 (3.7%) | |
| Diabetes, n (%) | 21 (33.9%) | 41 (55.4%) | 59 (55.7%) | 58 (41.4%) | 13 (24.1%) | <0.001 |
| Ischemic heart disease, n (%) | 10 (16.1%) | 24 (32.4%) | 37 (34.9%) | 64 (45.7%) | 22 (40.7%) | 0.004 |
| Neoplasia, n (%) | 5 (8.1%) | 13 (17.6%) | 17 (16.0%) | 31 (22.1%) | 7 (13.0%) | 0.201 |
| BMI (kg/m2), median (IQR) | 28.0 (9.8) | 29.1 (10.2) | 29.6 (8.8) | 27.8 (5.5) | 25.7 (6.2) | 0.002 |
| BMI classifications, n (%) | <0.001 | |||||
| <20 kg/m2 | 5 (8.1%) | 5 (6.8%) | 2 (1.9%) | 4 (2.9%) | 5 (9.6%) | |
| 20–25 kg/m2 | 15 (24.2%) | 19 (25.6%) | 20 (18.9%) | 25 (17.9%) | 18 (34.6%) | |
| 25–30 kg/m2 | 17 (27.4%) | 18 (24.3%) | 34 (32.1%) | 67 (47.9%) | 18 (34.6%) | |
| 30–35 kg/m2 | 12 (19.4%) | 17 (23.0%) | 26 (24.5%) | 33 (23.5%) | 8 (15.4%) | |
| ≥35 kg/m2 | 13 (21.0%) | 15 (20.3%) | 24 (22.6%) | 11 (7.8%) | 3 (5.8%) |
IQR: interquartile range; BMI: body mass index; CCI: Charlson Comorbidity Index; MIS: Malnutrition-Inflammation Score; SGA: Subjective Global Assessment. MIS and SGA are routinely assessed in all patients. However, 4 patients did not have complete MIS, SGA and BMI data (2 patients with missing MIS and SGA and 2 patients with missing BMI), mainly because the three indexes are calculated on the basis of an extensive clinical and biochemical evaluation, usually performed in the day hospital, after a first nephrology consultation. The missing data therefore regard either patients in the evaluation phase, or those who came to only one consultation. Four patients who alternated between CKD stages 2 and 3A, were considered CKD stage 3A. In bold, significant differences.