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. 2021 Dec 14;11(12):3391. doi: 10.3390/nano11123391

Table 1.

Proniosomes’ drug delivery applications.

Composition Cargo Application Reference
Cholesterol, Span 60 and maltodextrin Aceclofenac Anti-inflammatory in osteoarthritis [12]
Cholesterol, Span 60, maltodextrin and stearylamine Acemetacin Anti-inflammatory [13]
Cholesterol, lecithin, Span 60 and Span 40 Atenolol Hypertension treatment [14]
Cholesterol, lecithin and Tween 80 Atorvastatin calcium Anti- hyperlipidemic [15]
Cholesterol, lecithin and Span 40 Boswellic acid Anti-inflammatory [16]
Cholesterol, lecithin and Span 60 Caffeine Migraine treatment [17]
Cholesterol and Span 60 Cilostazole Anti-platelet [18]
Cholesterol, lecithin and Span 60 Clozapine Treatment of psychiatric disorders [19]
Cholesterol, lecithin and cremophor RH Curcumin Against ocular inflammation [20]
Cholesterol, Span 60 and Tween 80 Ciprofloxacin Anti-inflammatory [6]
Cholesterol, Span 40 TPGS Docetaxel Anticancer treatment [21]
Cholesterol and Span 60 Famotidine H2 receptor antagonist [22]
Cholesterol, Sorbitol and Span 80 Flurbiprofen Anti-inflammatory [23]
Cholesterol and Brij35 D-limonene Cancer therapy [24]
Cholesterol, Span 60 Itroconazole Antimicotic against candida albicans [25]
Cholesterol, lecithin and cremophor RH 40 Lacidipine Treatment of hypertension and atherosclerosis [26]
Cholesterol, Tween 80, sorbitol and sucrose Letrozole Breast cancer [27]
Cholesterol, Span 80 and lecithin Lignocaine Hydrochloride Dental anesthesia [28]
Cholesterol, Span 60 and Tween 60 Lomefloxacin HCl Treatment of bacterial conjunctivitis [29]
Cholesterol, lecithin and Lutrol F68 Lornoxicam Anti-inflammatory for rheumatoid arthritis, osteoarthritis and surgeries [30]
Cholesterol, lecithin and Span 60 Embelin Analgesic and anti-inflammatory [31,32]
Span 40, Span 60, and Brij series 72 Fluconazole Management of dental pain [33]
Cholesterol, lecithin and Span 60 Naproxen Anti-inflammatory [32]
Cholesterol, Span 60 and maltodextrin Pentazocine Management of cancer pain [34]
Cholesterol, Span 60, maltodextrin, pullulan and DPPH Resveratrol Controlling free radicals causing oxidative stress-induced cardiovascular diseases, atherosclerosis, cancer [35]
Cholesterol, Span 60, lecithin and stearylamine Risperidone Treatment of schizophrenia and other psychiatric disorders [36]
Cholesterol, lecithin and Span 80 Tramadol Anti-inflammatory and antinociceptive [37]
Cholesterol, Span 60, lactose and mannitol Vismodegib Carrier for the pulmonary route [38]