Table 3.
Ethosomes’ drug delivery applications.
| Composition | Cargo | Application | Reference |
|---|---|---|---|
| Soy lecithin | 5-Aminolevulinic acid | Treatment of hypertrophic scars | [110] |
| Soy phosphatidylcholine | 5-fluorouracil | Treatment of skin cancers | [111,112] |
| Soy lecithin and cholesterol | Apixaban | Anticoagulant | [113] |
| Soy phosphatidylcholine | Azelaic acid | Treatment of acne | [114] |
| Soy phosphatidylcholine and cholesterol | Boswellic acid | Anti-inflammatory | [115] |
| Phosphatidylcholine | Caffeic acid | Antioxidant | [116] |
| Soy lecithin | Curcumin and glycyrrhetinic acid | Psoriasis treatment | [117] |
| DSPE-PEG2000, hydrogenated soy phospholipids and cholesterol | Curcumin, hyaluronic acid and CD44 | Psoriasis treatment | [118] |
| Soy phosphatidylcholine, polyethylenimine and sodium cholate | Doxorubicin and curcumin | Melanoma treatment | [119] |
| Lecithin and Tween 80 | Fenretinide | Chemopreventive for breast cancer | [120] |
| Soy phosphatidylcholine, cremophor-A25 and chitosan | Ferrous chlorophyllin | Photodynamic therapy for the treatment of squamous cell carcinoma | [121] |
| Phospholipid 90G | Fisetin | Skin cancers treatment | [122] |
| Soy phosphatidylcholine | Flurbiprofen | Anti-inflammatory | [123] |
| Soy phosphatidylcholine | Griseofulvin | Antifungal treatment | [124] |
| Cholesterol and lecithin | Hyaluronic acid | Transdermal delivery of drugs | [125] |
| Soy phosphatidylcholine, cholesterol | HRP IgG | Transdermal delivery of vaccines | [126] |
| Soy phosphatidylcholine, cholesterol and deoxycholic acid | Indomethacin | Treatment of pain and inflammation in rheumatoid arthritis | [127] |
| Soy lecithin and cholesterol | Luteolin | Anti-tumor activity in hepatocellular carcinoma | [128] |
| Soy lecithin | Methotrexate | Treatment of psoriasis | [129] |
| Soy phosphatidylcholine | Methoxsalen | Treatment of vitiligo | [130] |
| Soy phosphatidylcholine, cholesterol and mannitol | Paenolol | Anti-inflammatory, antidiabetic and pain-relieving | [131] |
| Soy phosphatidylcholine | Paeoniflorin | Arthritis therapy | [132] |
| Soy phosphatidylcholine and cholesterol | Phenylethyl resorcinol | Skin Lightening Applications | [133] |
| Soy phosphatidylcholine, stearylamine and propylene glycol | Resveratrol | Antioxidant | [134] |
| Phosphatidylcholine | Retinyl palmitate | Acne treatment | [135] |
| Soy phosphatidylcholine | Sulforaphane | Treatment of skin cancers | [136] |
| Soy phosphatidylcholine | Terbinafine hydrochloride | Antifungal treatment | [137] |
| Phospholipid 90G | Thymoquinone | Treatment of acne | [138] |
| Soy phosphatidylcholine and cholesterol | Thymosin β-4 | Wound repair | [139] |