Figure 4.

Selection and recombination events in the AgV2 lineage. (a) Estimated dN-dS ratios for the RABV N gene codons in the AgV2 lineage with the SLAC method. (b) Phylogenetic tree showing positively selected sites in the wild cycle and amino acid replacements along the entire phylogeny. Color-circled numbers represent positively selected codons identified by different methods (ancestral→derived states are shown). Black circles represent amino acid replacements. The numbers below these circles indicate the residue position. Curved arrows indicate lineages involved in the three bioinformatically confirmed recombination events (1, 2, and 4).