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. 2021 Dec 17;9(12):1496. doi: 10.3390/vaccines9121496

Table 2.

Odds ratios from multilevel logistic regression analyses of reporting side effects after COVID-19 vaccination adjusted for age, sex, first or second injection, and type of vaccine (n = 266) (COVID-PCD study, May 2021).

OR Lower 95% CI Upper 95% CI p-Value
No side effects
Age (continuous, per year increase) 0.98 0.95 1.00 0.126
Sex (female vs. male) 1.80 0.72 4.50 0.208
Injection (second vs. first) 1.57 0.79 3.11 0.198
Vaccine (ref: Pfizer-BioNTech)
Moderna 2.34 0.61 8.97 0.215
AstraZeneca 0.89 0.33 2.42 0.818
Local pain/swelling
Age (continuous, per year increase) 0.99 0.96 1.01 0.320
Sex (female vs. male) 1.58 0.72 3.49 0.249
Injection (second vs. first) 1.45 0.86 2.45 0.168
Vaccine (ref: Pfizer-BioNTech)
Moderna 3.32 1.11 9.92 0.032
AstraZeneca 0.54 0.22 1.30 0.167
Tiredness
Age (continuous, per year increase) 0.99 0.97 1.01 0.374
Sex (female vs. male) 1.54 0.81 2.93 0.190
Injection (second vs. first) 2.19 1.33 3.61 0.002
Vaccine (ref: Pfizer-BioNTech)
Moderna 2.95 1.23 7.09 0.016
AstraZeneca 1.12 0.55 2.29 0.751
Fever
Age (continuous, per year increase) 0.97 0.95 0.99 0.015
Sex (female vs. male) 0.90 0.43 1.90 0.791
Injection (second vs. first) 3.12 1.64 5.94 0.001
Vaccine (ref: Pfizer-BioNTech)
Moderna 5.64 2.06 15.42 0.001
AstraZeneca 7.57 2.93 19.53 <0.001
Headache
Age (continuous, per year increase) 0.98 0.96 1.00 0.052
Sex (female vs. male) 1.73 0.83 3.62 0.147
Injection (second vs. first) 2.31 1.33 4.00 0.003
Vaccine (ref: Pfizer-BioNTech)
Moderna 3.15 1.21 8.20 0.019
AstraZeneca 6.30 2.65 15.00 <0.001
Muscle/bone pain (not around injection site)
Age (continuous, year increase) 0.97 0.95 0.99 0.003
Sex (female vs. male) 0.79 0.45 1.38 0.403
Injection (second vs. first) 1.59 0.99 2.56 0.057
Vaccine (ref: Pfizer-BioNTech)
Moderna 2.34 1.11 4.96 0.026
AstraZeneca 4.73 2.34 9.53 <0.001
Other
Age (continuous, per year increase) 1.01 0.97 1.04 0.751
Sex (female vs. male) 1.34 0.45 4.01 0.604
Injection (second vs. first) 0.68 0.78 3.61 0.183
Vaccine (ref: Pfizer-BioNTech)
Moderna 3.93 0.95 16.19 0.058
AstraZeneca 4.22 1.24 14.38 0.021