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. 2021 Dec 20;22(24):13656. doi: 10.3390/ijms222413656

Figure 2.

Figure 2

Neuropeptides secreted by i-NANC (VIP) and e-NANC (SP, NKA) efferent fibers of the vagus nerve and returning collaterals of vagus nerve sensory fibers (SP, NKA and CGRP) in the course of asthma; (−) means smooth muscle retraction and bronchodilation; (+) means smooth muscle contraction, bronchoconstriction, mucus hypersecretion, plasma exudation and edema.