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. 2021 Dec 13;8(12):181. doi: 10.3390/jcdd8120181

Table 3.

Lipid profiles for the different LPA genotype and haplotype subgroups.

Parameter Subgroup p Value
rs10455872 A/A A/G G/G
Total cholesterol (mmol/L) 4.2 ± 0.8 4.2 ± 0.8 4.7 ± 1.3 0.402
LDL (mmol/L) 2.3 ± 0.7 2.3 ± 0.7 2.7 ± 1.4 0.496
HDL (mmol/L) 1.1 ± 0.2 1.2 ± 0.3 1.3 ± 0.1 0.237
Triglycerides (mmol/L) 1.7 ± 0.9 1.6 ± 0.8 1.7 ± 0.7 0.927
Apolipoprotein A1 (g/L) 1.3 ± 0.1 1.4 ± 0.2 1.4 ± 0.1 0.132
Apolipoprotein B (g/L) 0.8 ± 0.2 0.8 ± 0.2 0.8 ± 0.2 0.869
rs3798220 T/T T/C C/C
Total cholesterol (mmol/L) 4.2 ± 0.9 4.4 ± 0.7 4.1 0.386
LDL (mmol/L) 2.3 ± 0.8 2.4 ± 0.6 2.3 0.404
HDL (mmol/L) 1.1 ± 0.2 1.2 ± 0.3 1.1 0.663
Triglycerides (mmol/L) 1.7 ± 0.8 1.7 ± 1.0 1.4 0.910
Apolipoprotein A1 (g/L) 1.3 ± 0.2 1.3 ± 0.2 1.2 0.923
Apolipoprotein B (g/L) 0.8 ± 0.2 0.8 ± 0.2 0.9 0.581
Haplotype AT no AT one AT two AT
Total cholesterol (mmol/L) 4.5 ± 1.1 4.3 ± 0.8 4.0 ± 0.9 0.229
LDL (mmol/L) 2.5 ± 1.1 2.4 ± 0.7 2.1 ± 0.8 0.329
HDL (mmol/L) 1.3 ± 0.2 1.2 ± 0.3 1.1 ± 0.2 0.116
Triglycerides (mmol/L) 1.5 ± 0.6 1.7 ± 0.9 1.7 ± 0.9 0.799
Apolipoprotein A1 (g/L) 1.4 ± 0.2 1.3 ± 0.2 1.3 ± 0.1 0.257
Apolipoprotein B (g/L) 0.8 ± 0.2 0.8 ± 0.2 0.8 ± 0.2 0.960
Haplotype AC no AC one AC two AC
Total cholesterol (mmol/L) 4.2 ± 0.9 4.4 ± 0.7 4.1 0.710
LDL (mmol/L) 2.3 ± 0.8 2.4 ± 0.6 2.3 0.750
HDL (mmol/L) 1.2 ± 0.2 1.2 ± 0.3 1.1 0.889
Triglycerides (mmol/L) 1.7 ± 0.8 1.7 ± 1.0 1.4 0.933
Apolipoprotein A1 (g/L) 1.3 ± 0.2 1.3 ± 0.2 1.2 0.781
Apolipoprotein B (g/L) 0.8 ± 0.2 0.8 ± 0.2 0.9 0.794
Haplotype GT no GT one GT two GT
Total cholesterol (mmol/L) 4.2 ± 0.8 4.2 ± 0.8 4.7 ± 1.3 0.402
LDL (mmol/L) 2.3 ± 0.7 2.3 ± 0.7 2.7 ± 1.4 0.496
HDL (mmol/L) 1.1 ± 0.2 1.2 ± 0.3 1.3 ± 0.1 0.237
Triglycerides (mmol/L) 1.7 ± 0.9 1.6 ± 0.8 1.7 ± 0.7 0.927
Apolipoprotein A1 (g/L) 1.3 ± 0.1 1.4 ± 0.2 1.4 ± 0.1 0.152
Apolipoprotein B (g/L) 0.8 ± 0.2 0.8 ± 0.2 0.8 ± 0.2 0.869

Data are means ± standard deviations. p values for rs3798220 and haplotype AC were obtained using Student’s t tests. Other p values were obtained using one-way ANOVA. LDL, low-density lipoprotein; HDL, high-density lipoprotein.