Table 1.

Reviews that provided a focused discussion on urine EVs’ application in PCa diagnosis.

Authors	Summary
Salciccia et al., 2021 [28]	biomarkers in PCa diagnosis including those derived from urine EVs compiled all clinical approved diagnostic kits for PCa
Drake and Kislinger, 2014 [29]	proteomics based PCa associated exosomes and their potential applications the EV proteome in PCa diagnosis
Nawaz et al., 2014 [30]	roles of extracellular vesicles in the most common urogenital cancers (prostate, kidney and bladder) EV isolation methods
Wang et al., 2020 [31]	exosome isolation techniques exosomal protein biomarker studies
Wu et al., 2019 [32]	EVs’ biophysical properties, roles and applications in the most common urologic neoplasms