Table 2.

Animal models for Mucopolysaccharidosis type VI. ENU = N-ethyl-N-nitrosourea.

Year of Publication	Animal Model	Model Generation	Reference
1977	Siamese cat	Spontaneous	[64]
1993	Rat	Spontaneous	[127]
1996	Mouse	Targeted disruption	[122]
2009	Mouse	ENU mutagenesis	[123]
2012	Miniature Poodle dog	Spontaneous	[128]
2015	Miniature Schnauzer dog	Spontaneous	[129]
2018	Great Dane dog	Spontaneous	[124]