Figure 1.
Tyr synthesis (solid line) and Tyr catabolism (dashed line). Enzymes: chorismate mutase (CM), prephenate aminotransferase (PPA-AT), arogenate dehydrogenase (ADH), prephenate dehydrogenase (PDH), Tyr aminotransferase (Tyr-AT), 4-hydroxyphenylpyruvate dioxygenase (HPPD), homogentisate 1,2-dioxygenase (HGO), maleylacetoacetate isomerase (MAAI), fumarylacetoacetate hydrolase (FAH). Substrates or products: p-hydroxyphenylpyruvate (HPP), homogentisate (HGA). According to [4] with some modifications.