Table 1.
HPV genera and properties.
| Genus | Biological and Clinical Aspects |
|---|---|
|
Alpha-
papillomavirus |
Mucosal and cutaneous lesions Comprised of 14 species (α1–α14) that include 65 HPV types [8] Molecular genotyping of HPV L1 gene in low-risk and high-risk groups |
|
Beta-
papillomavirus |
Cutaneous lesions Comprised of 5 species (β1–β5) that include 54 HPV types [9] Reports of beta HPV in mucosal epithelia [10,11] Etiological role in non-melanoma skin cancer [12] Promotes the development of cSCC in EV patients [13] |
|
Gamma-
papillomavirus |
Cutaneous lesions Comprised of 27 species (γ1–γ5) that include 98 HPV types [9] Reports of gamma HPV in mucosal epithelia [14,15] |
|
Mu-
papillomavirus |
Cutaneous lesions Includes 3 HPV types [16] |
|
Nu-
papillomavirus |
Cutaneous lesions Includes 1 HPV type [16] |
L1 = major capsid protein; cSCC = cutaneous squamous cell carcinoma; EV = epidermodysplasia verruciformis.