Skip to main content
. 2021 Dec 4;13(12):2440. doi: 10.3390/v13122440

Figure 2.

Figure 2

Neutralizing activity of sera from CoronaVac-vaccinated individuals. Serial dilutions of serum samples were prepared, and neutralization activity was evaluated against (A) WT SARS-CoV-2, and (B) Gamma and (C) Zeta variants at 1, 3, and 6 months after second dose. Nonlinear regression curves generated with a maximum of 1000 interactions and 95% confidence interval. Error bars delimited by colors. Multiple comparisons were performed by two-way ANOVA followed by Sidak’s post hoc test. Asterisks, significance difference compared to 1-month group. * p < 0.05; ** p < 0.001; *** p < 0.0001. (D) PRNT50 neutralizing titers of WT SARS-CoV-2, and Gamma and Zeta variants using sera from vaccinated individuals collected at different time points, indicated by black (prevaccination), purple (1 month), turquoise (3 months), and red (6 months). Multiple comparisons were performed by one-way ANOVA followed by Tukey’s post hoc test. * p < 0.05; ** p < 0.001. PRNT50 = 50% plaque reduction neutralization test; n.s.= not statistically significantly; LOD = limit of detection.