Table 1.
Baseline characteristics of subjects.
| Variables | Familial Hypercholesterolemia | Healthy (n = 20) |
p-Value | ||
|---|---|---|---|---|---|
| HoFH (n = 18) | HeFH (n = 18) | ||||
| Sex | Male | 8 (44.4%) | 10 (55.6%) | 9 (45.0%) | 0.751 |
| Female | 10 (55.6%) | 8 (44.4%) | 11 (55.0%) | ||
| Age (y) | 13.10 ± 2.95 | 31.60 ± 2.00 a | 34.50 ± 1.70 a | <0.001 | |
| TC (mmol/L) | 16.03 ± 1.13 | 6.7 ± 0.50 a | 4.02 ± 0.13 a,b | <0.001 | |
| TG (mmol/L) | 2.60 ± 0.33 | 1.23 ± 0.10 a | 1.04 ± 0.10 a | 0.001 | |
| HDL-C (mmol/L) | 1.60 ± 0.13 | 1.73 ± 0.30 | 1.21 ± 0.10 | 0.064 | |
| LDL-C (mmol/L) | 11.01 ± 1.00 | 4.61 ± 0.50 a | 2.41 ± 0.20 a | <0.001 | |
Data are shown as Mean ± SE; a: Significant in comparison with HoFH group; b: Significant in comparison with HeFH group. HDL-C: High-density lipoprotein cholesterol; HeFH: Heterozygous familial hypercholesterolemia; HoFH: Homozygous familial hypercholesterolemia; LDL-C: Low-density lipoprotein cholesterol; mmol/L: Millimoles per liter; TC: Total cholesterol; TG: Triglyceride; y: Year.