Table 3.
Group differences for MMN and P3a. Age and gender as covariates.
| MMN-P3a Amplitude | HCs (n = 61) |
SCZ-A (n = 23) |
SCZ-B (n = 38) |
SCZ-C (n = 27) |
SCZ-D (n = 29) |
F | p |
|---|---|---|---|---|---|---|---|
| d-MMN | −5.51 ± 2.47 | −3.456 ± 1.83 | −3.87 ± 2.05 | −3.55 ± 1.71 | −3.208 ± 1.99 | 8.274 | <0.001 * |
| p-MMN | −3.50 ± 1.56 | −2.43 ± 1.129 | −2.70 ± 1.29 | −2.11 ± 0.930 | −2.35 ± −1.19 | 7.533 | <0.001 * |
| d-P3a | 2.95 ± 1.95 | 2.02 ± 1.81 | 2.54 ± 1.79 | 2.13 ± 1.11 | 1.53 ± 1.21 | 2.5 | 0.04 ** |
| p-P3a | 1.52 ± 1.05 | 1.40 ± 1.26 | 1 ± 1.16 | 0.95 ± 0.87 | 0.70 ± 1.01 | 2.1 | 0.078 |
HCs, healthy controls; SCZ, subjects with schizophrenia; d-MMN, duration deviant MMN; p-MMN, pitch deviant MMN; d-P3a: duration deviant P3a; p-P3a, pitch deviant P3a. p values in bold indicate statistical significance (significant p-value threshold 0.002). Post-hoc pairwise comparisons: * All SCZ groups had reduced d-MMN (all p < 0.001) and p-MMN (SCZ-A< HCs, p = 0.01; SCZ-B < HCs, p = 0.03; SCZ-C and SCZ-D< HCs, p < 0.001) amplitude compared to HCs; ** SCZ-D had reduced d-P3a amplitude compared to HCs (p = 0.003).