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. 2021 Dec 18;22(24):13599. doi: 10.3390/ijms222413599

Figure 5.

Figure 5

Changes in the level of (A) protein kinase A (PKA) and (B) protein kinase C (PKC) in response to magnesium (Mg2+), morphine (MRF) and the combination of these substances (Mg2+ + MRF) in periaqueductal gray matter (PAG) lysate from streptozotocin (STZ)-treated rats. Results are presented as means ± SEM. Statistical analysis was performed using one-way ANOVA followed by Dunnett’s post-hoc test. *** p < 0.001; ** p < 0.01; * p < 0.05 vs. STZ; ### p < 0.001; ## p <0.01, # p < 0.05; vs. STZ + MRF; &&& p < 0.001, && p < 0.01 vs. STZ + Mg2+; n = 6 rats/group.