Figure 3.

Correlation matrix of activation in systemic parameters. Complement activation products, C5a and TCC, and NETs release correlated with common inflammation and coagulation markers in mechanically ventilated patients with SARS-CoV-2 infection. Correlation coefficient was assessed using the Spearman rank correlation test. Values indicate Spearman r. CRP, C-reactive protein; PCT, procalcitonin; IL-6, interleukin 6; WBC, white blood cell count; INR, international normalized rate; TCC, terminal complement complex; NETs, neutrophilic extracellular traps. * p < 0.002 (significant after Bonferroni correction).