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. 2021 Dec 17;13(12):2537. doi: 10.3390/v13122537

Figure 2.

Figure 2

Increased surface expression of angiotensin converting enzyme 2 (ACE2) (a), toll-like receptor 2 (TLR2) (b), and TLR4 (c) in the bronchial (bro-ALI) and alveolar (alv-ALI) mucosa model developed at air–liquid interface. Both bro-ALI and alv-ALI were exposed to 10 nM recombinant SARS-CoV-2 spike glycoprotein S1 (S1 protein) for 6 h and compared to the corresponding sham. ACE2 (a), TLR2 (b), and TLR4 (c) were measured by flow cytometry and data are presented as median fluorescent intensity (MFI) and interquartile range. n = 6 per exposure condition; * significance: p < 0.05 (Mann–Whitney U test).