Figure 6.
GPC promotes atherosclerosis. (A,B) Representative Oil-red-O/haematoxylin-stained aortic root sections from male (A) and female (B) C57BL/6J Apoe−/− mice fed control or GPC supplemented chow diets, scale bar = 0.2 mm. (C,D) Aortic lesion area in 20-week-old male (C) and female (D) C57BL/6J Apoe−/− mice fed GPC supplemented chow diet versus control chow diet. p values were calculated by Wilcoxon rank sum test. (E,F) Pearson correlation of aortic lesion to plasma TMAO in 20-week-old male and female C57BL/6J Apoe−/− mice fed either GPC supplemented chow diet or control chow diet for 16 weeks.