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. 2021 Dec 20;22(24):13634. doi: 10.3390/ijms222413634

Figure 2.

Figure 2

Changes in proliferation of the Caco-2 cell line after incubation with 50 ng/mL, 100 ng/mL, 150 ng/mL, and 200 ng/mL of histamine (A); 150 ng/mL, 300 ng/mL, and 450 ng/mL of FXF (C); 150 ng/mL, 300 ng/mL and 450 ng/mL of osthole (D); and with mixtures of 150 ng/mL of histamine and 450 ng/mL of FXF or osthole (B). The symbols show the mean and the bars depict the standard deviation. Statistically significant differences compared to control, i.e., cells cultured in medium (p < 0.05, two-way ANOVA with Dunnett’s multiple comparisons test) are shown in rectangles with dotted edges. The analyzes were performed in triplicate in two independent experiments.