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Effect of antibiotics mixture on bone homeostasis. Mice were orally administered antibiotics or vehicle for four weeks. (A–F): Body weight, tibial bone mineral density (B–D), serum bone formation marker (E), and serum bone resorption marker (F) at sacrifice. N = 7–10 per group. BMD: bone mineral density, CTX: C-terminal telopeptide of collagen, PINP: procollagen type I N-terminal propeptide. ** p < 0.01.
