Table 4.
Prevalence of elevated markers insulin resistance in relation to urinary iodine concentration in US adults, NHANES 2011–2012 1.
| Elevated IR Marker | Model | Low UIC (<100 µg/L) |
Normal UIC (≥100 µg/L) |
2p-Value |
|---|---|---|---|---|
| OR (95% CI) | Referent | |||
| FPG ≥ 5.6 mmol/L | 1 | 1.08 (0.72–1.62) | 1 | 0.7036 |
| 2 | 1.11 (0.77–1.59) | 1 | 0.5630 | |
| Insulin > 9 μU/mL | 1 | 0.99 (0.60–1.65) | 1 | 0.1877 |
| 2 | 0.99 (0.59–1.67) | 1 | 0.9926 | |
| HOMA-IR ≥ 2.6 | 1 | 0.86 (0.55–1.34) | 1 | 0.4744 |
| 2 | 0.83 (0.56–1.25) | 1 | 0.3489 | |
| HbA1c ≥ 5.7% | 1 | 0.83 (0.57–1.21) | 1 | 0.3091 |
| 2 | 0.91 (0.64–1.28) | 1 | 0.5502 |
1 Data are from the National Health and Nutrition Examination Survey. 2 Multiple logistic regression analysis was performed to estimate odds ratio for elevated marker of insulin resistance in female adults from NHANES 2011–2012 in two models: unadjusted (model 1) and adjusted (model 2). See Table 5 for p values of the covariates used in model 2. IR, insulin resistance; UIC, urinary iodine concentration; OR, odds ratio; CI, confidence interval; FPG, fasting plasma glucose; HbA1c, glycated hemoglobin A1C; HOMA-IR, homeostatic model assessment of insulin resistance.