Table 6.
Prevalence of elevated markers insulin resistance in relation to urinary iodine concentration in US female adults, NHANES 2011–2012 1.
| Elevated IR Marker | Model | Low UIC (<100 µg/L) |
Normal UIC (≥100 µg/L) |
2p-Value |
|---|---|---|---|---|
| OR (95% CI) | Referent | |||
| FPG ≥ 5.6 mmol/L | 1 | 1.52 (0.94–2.44) | 1 | 0.0839 |
| 2 | 1.73 (1.09–2.72) | 1 | 0.0211 * | |
| Insulin > 9 μU/mL | 1 | 1.04 (0.58–1.87) | 1 | 0.8873 |
| 2 | 1.08 (0.54–2.16) | 1 | 0.8120 | |
| HOMA-IR ≥ 2.6 | 1 | 0.91 (0.46–1.80) | 1 | 0.7734 |
| 2 | 0.56 (0.32–0.99) | 1 | 0.0478 * | |
| HbA1c ≥ 5.7% | 1 | 0.56 (0.34–0.90) | 1 | 0.0208 * |
| 2 | 0.58 (0.34–1.02) | 1 | 0.0563 |
1 Data are from the National Health and Nutrition Examination Survey. 2 Multiple logistic regression analysis was performed to estimate odds ratio for elevated marker of insulin resistance in female adults from NHANES 2011–2012 in two models: unadjusted (model 1) and adjusted (model 2). (* p < 0.05). See Table 5 for p values of the covariates used in model 2. IR, insulin resistance; UIC, urinary iodine concentration; OR, odds ratio; CI, confidence interval; FPG, fasting plasma glucose; HbA1c, glycated hemoglobin A1C; HOMA-IR, homeostatic model assessment of insulin resistance. The p-values for covariates controlled for in the adjusted model are shown for each marker of IR in adult females are shown in Table 5.