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Histologial evaluation of liver, pancreas, and brow fat pad in mice after 3 weeks of experiment. (A)—C57Bl/6 (healthy control), (B)—AY mice (untreated), (C)—AY mice treated by metformin at a dose of 250 mg/kg, (D)—AY mice treated by SHE-196 at a dose of 15 mg/kg. Hematoxylin and eosin staining, ×200.
