Figure 2.

Duodenal architectural parameters assessed in 5xFAD mice after FMT. (a) Duodenal sections were stained with HE and villus length (b), crypt depth (c), submucosal thickness (d), and muscularis thickness (e) measured. Exemplary sections are shown for each group. Two slides per animal (n = 10 animals per group; 5 female) were used and four villi and neighboring structures taken into account per slide. (*, p < 0.05). Data are presented as mean ± SEM. Single data points present the mean of all technical values derived from one animal (“young”: 5xFAD treated with cecal material from young wt mice; “old”: 5xFAD treated with cecal material from old wt mice).