Table 1.
Total Number of Observations b n = 6661 |
With PDR to Any Drug c,d n = 957 |
p Value | With PDR to EFV/NVP d n = 690 |
p Value | |
---|---|---|---|---|---|
Gender, n (%) Cisgender Women Cisgender Men Transgender Women Transgender Men Missing |
267 (4.0) 6234 (93.6) 51 (0.8) 3 (0.0) 106 (1.6) |
32 (12.0) 907 (14.5) 6 (11.8) 0 (0.0) 12 (11.3) |
0.14 0.06 0.39 0.62 0.23 |
24 (9.0) 653 (10.5) 4 (7.8) 0 (0.0) 9 (8.5) |
0.26 0.13 0.38 0.72 0.33 |
Age (years) e Median (IQR) |
28 (24–35) |
28 (24–34) |
0.09 |
28 (24–34) |
0.30 |
State of residence, n (%) Mexico City Mexico State Other Missing |
4223 (63.4) 967 (14.5) 90 (1.4) 1381 (20.7) |
621 (14.7) 142 (14.7) 9 (10.0) 185 (13.4) |
0.16 0.40 0.15 0.13 |
448 (10.6) 107 (11.1) 5 (5.6) 130 (9.4) |
0.20 0.23 0.08 0.10 |
HIV subtype, n (%) B Non-B |
6577 (98.7) 84 (1.3) |
946 (14.4) 11 (13.1) |
0.44 |
680 (11.6) 10 (11.9) |
0.37 |
Viral load (log RNA copies/mL) f Median (range) |
4.8 (4.25–5–31) |
4.7 (4.2–5.3) |
0.02 * |
4.7 (4.2–5.3) |
0.03 * |
CD4+ T cell count (cells/mm3), n g Median (IQR) |
249 (120–395) |
250 (123–407) |
0.22 |
254 (129–405) |
0.16 |
CD4+ T cell count category, n (%) <200 cells/mm3 200–500 cells/mm3 >500 cells/mm3 Missing |
2323 (34.87) 2721 (40.8) 809 (12.2) 808 (12.1) |
334 (14.4) 389 (14.3) 129 (15.9) 105 (13.0) |
0.51 0.46 0.10 0.13 |
240 (10.3) 285 (10.5) 94 (11.6) 71 (8.8) |
0.50 0.41 0.12 0.06 |
CD4+ T cell %, n h Median (IQR) |
15 (9–21) |
15 (9–22) |
0.27 |
15 (10–22) |
0.14 |
a Data for 6661 participants enrolled from January 2017 to December 2020. b Column percentages are shown. c Using the WHO definition for PDR (see Methods). d Row percentages are shown. e Data missing for 114 participants (n = 6547). f Data missing for 557 participants (n = 6104). g Data missing for 808 participants (n = 5853). h Data missing for 2234 participants (n = 4427). * p < 0.05. PDR; pretreatment drug resistance; EFV, efavirenz; NVP, nevirapine; IQR, interquartile range.