. 2021 Nov 23;14(12):1205. doi: 10.3390/ph14121205

Table 1.

Influence of mobile phase composition in TXA-ACN protonated adduct formation.

ACN Mobile Phase Composition (%, v/v)	[M + H]⁺/[M + ACN + H]⁺ Ratio (%)
ACN Mobile Phase Composition (%, v/v)	Flow Injection	Chromatography
80	21.4 ± 1.5 ^I	10.5 ± 0.1 ^II
70	29.0 ± 1.9 ^III	23.3 ± 1.4 ^IV
60	39.4 ± 2.4 ^V	29.5 ± 1.7 ^VI
50	54.7 ± 4.2 ^VII	33.8 ± 0.1 ^VIII

^I–VIII Comparison between the mean ratio [M + H]⁺/[M + ACN + H]⁺ values obtained using flow injection analysis and chromatography. Different superscript numbers indicate that statistically significant differences were observed (p < 0.05).