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. 2021 Dec 10;22(24):13293. doi: 10.3390/ijms222413293

Figure 1.

Figure 1

Domain structures of mouse AhR. The AhR protein contains several critical domains. DNA binding domain:The basic region helix–loop–helix (bHLH) aids in binding the transcription factor to DNA and protein–protein interactions; Ligand binding domain: PAS B domain along with flanking amino acid residues on both sides, serves as ligand-binding domains, and mediates interactions with several other proteins;. Transcriptional activation binding domain: In the C-terminal region, a glutamine-rich domain is involved in coactivator recruitment and transactivation.