Table 1.
Pharmacological Activity |
Tested Substance | In Vitro/ In Vivo |
Model | Dose/Concentration | Ref. |
---|---|---|---|---|---|
Antioxidant | Aqueous extract | In vivo | Wister albino rats | 400 and 800 mg/kg | [36] |
Fruit extract | In vitro | - | 1.5 mM | [37] | |
Garcinol-enriched fraction | In vivo | C57BL/6 male mice | 25, 50, and 100 mg/kg | [38] | |
Aqueous extract | In vitro | - | - | [39] | |
In vivo | Wister albino rats | 250 and 500 mg/kg | |||
G. indica fruit rind powder | In vivo | Swiss albino mice, Wister rats | 0.5, 1, and 2% w/w | [40] | |
Anti-obesity | Garcinol-enriched fraction | In vivo | C57BL/6 male mice | 25, 50, and 100 mg/kg | [38] |
Fruit extract | In vitro | 3T3-L1 preadipocytes | 1 and 2 µg/mL | [41] | |
In vivo | C57BL/6 male mice | 0.01% w/w | |||
Anti-arthritic | Garcinol-enriched fraction | In vivo | Male Wistar rats | 10 mg/kg | [42] |
Anti-inflammatory | Garcinol-enriched fraction | In vivo | C57BL/6 male mice | 25, 50, and 100 mg/kg | [38] |
Antidepressant and anxiolytic effect |
G. indica fruit rind powder | In vivo | Swiss albino mice, Wister rats | 0.5, 1, and 2% | [40] |
Antibacterial | Fruit extract | In vitro | - | 1.5 mM | [37] |
Hepatoprotective | Aqueous extract | In vivo | Wister albino rats | 400 and 800 mg/kg | [36] |
Cardioprotective | Garcinol-enriched fraction | In vivo | C57BL/6 male mice | 25, 50, and 100 mg/kg | [38] |
Aqueous extract | In vivo | Wister albino rats | 250 and 500 mg/kg | [39] |