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. 2021 Dec 20;14(12):1338. doi: 10.3390/ph14121338

Table 1.

Summary of pharmacological studies for Garcinia indica.

Pharmacological
Activity
Tested Substance In Vitro/
In Vivo
Model Dose/Concentration Ref.
Antioxidant Aqueous extract In vivo Wister albino rats 400 and 800 mg/kg [36]
Fruit extract In vitro - 1.5 mM [37]
Garcinol-enriched fraction In vivo C57BL/6 male mice 25, 50, and 100 mg/kg [38]
Aqueous extract In vitro - - [39]
In vivo Wister albino rats 250 and 500 mg/kg
G. indica fruit rind powder In vivo Swiss albino mice, Wister rats 0.5, 1, and 2% w/w [40]
Anti-obesity Garcinol-enriched fraction In vivo C57BL/6 male mice 25, 50, and 100 mg/kg [38]
Fruit extract In vitro 3T3-L1 preadipocytes 1 and 2 µg/mL [41]
In vivo C57BL/6 male mice 0.01% w/w
Anti-arthritic Garcinol-enriched fraction In vivo Male Wistar rats 10 mg/kg [42]
Anti-inflammatory Garcinol-enriched fraction In vivo C57BL/6 male mice 25, 50, and 100 mg/kg [38]
Antidepressant and
anxiolytic effect
G. indica fruit rind powder In vivo Swiss albino mice, Wister rats 0.5, 1, and 2% [40]
Antibacterial Fruit extract In vitro - 1.5 mM [37]
Hepatoprotective Aqueous extract In vivo Wister albino rats 400 and 800 mg/kg [36]
Cardioprotective Garcinol-enriched fraction In vivo C57BL/6 male mice 25, 50, and 100 mg/kg [38]
Aqueous extract In vivo Wister albino rats 250 and 500 mg/kg [39]