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Probability of target attainment (PTA) of AUC24 h/MIC > 33.4 after loading and on Day 7 associated with isavuconazole maintenance doses of 100, 200 and 300 mg daily (solid lines) against the EUCAST MIC distribution (histograms) of A. fumigatus (a) and A. flavus (b). Horizontal dotted lines identify the threshold for optimal PTA (90%).
