. 2021 Dec 13;13(12):2143. doi: 10.3390/pharmaceutics13122143

Table 5.

Drug release kinetics.

Model	Zero Order		First Order		Higuchi Model		Korsmeyer–Peppas Model
Criteria	R²	MSC	R²	MSC	R²	MSC	R²	MSC	n Value
Formulation	R²	MSC	R²	MSC	R²	MSC	R²	MSC	n Value
F2	0.6777	1.2998	0.9682	2.6653	0.5167	0.0553	0.9259	2.1537	0.215
F4	0.8940	1.9315	0.9902	4.3081	0.9655	3.0539	0.9858	3.7843	0.630
F6	0.7281	0.9723	0.9797	3.5694	0.9256	2.2687	0.9268	2.7314	0.528

R²—coefficient of determination; MSC—model selection criterion; n value—release exponent, indicating the drug-release mechanism.