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. 2021 Dec 10;15:782305. doi: 10.3389/fnhum.2021.782305

TABLE 3.

Summary of GRADE findings.

Certainty assessment
No. of patients
Certainty Importance
Outcomes Stimulation timing No. of studies Study design Risk of bias Inconsistency Indirectness Imprecision Other considerations Intervention group Control group
10 MWT Online 3 RCT Seriousa Not serious Not serious Not serious None 36 37 ⊕⊕⊕◯ Moderate Important
Offline 2 RCT Not serious Not serious Not serious Seriousf None 32 30 ⊕⊕⊕◯ Moderate Important
Total 5 RCT Seriousa Not serious Not serious Seriousf None 68 67 ⊕⊕◯◯ Low Important
6 MWT Online 2 RCT Seriousb Not serious Not serious Not serious None 20 20 ⊕⊕⊕◯ Moderate Important
Offline 2 RCT Not serious Not serious Not serious Seriousf None 32 30 ⊕⊕⊕◯ Moderate Important
Total 4 RCT Seriousb Seriousc Not serious Seriousf None 52 50 ⊕◯◯◯ Very low Important
FAC Online 1 RCT Seriousb N.A. Not serious Not serious None 10 10 N.A. Important
Offline 1 RCT Not serious N.A. Not serious Not serisous None 11 10 N.A. Important
Total 2 RCT Seriousb Seriousd Not serious Seriousf None 21 20 ⊕◯◯◯ Very low Important
Gait analysis (cadence) Online 2 RCT Seriousb Seriouse Not serious Seriousf None 20 20 ⊕◯◯◯ Very low Important
Offline
Total 2 RCT Seriousb Seriouse Not serious Seriousf None 20 20 ⊕◯◯◯ Very low Important
TUGT Online 1 RCT Seriousb N.A. Not serious Seriousf None 15 15 N.A. Important
Offline 1 RCT Not serious N.A. Not serious Seriousf None 21 20 N.A. Important
Total 2 RCT Seriousb Not serious Not serious Seriousf None 36 35 ⊕⊕◯◯ Low Important

N.A.: Not applicable, 10 MWT: 10-m walking test, 6 MWT: 6-min walking test, FAC: Functional ambulation category, TUGT: Timed up and go test, RCT: Randomized controlled trial.

aIndicating three studies with moderate risk of bias, bIndicating one study with moderate risk of bias, cI2 = 72%, dI2 = 87%, eI2 = 73%, and fWide 95% confidence interval.