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A genome-wide investigation in our in-house genome library, using the amino acid sequence MxYxH* (the asterisk represents a stop codon) and the DNA sequence of bytO homolog from Pyxidicoccus sp. CA032A as query, revealed a genetic operon in Pyxidicoccus fallax An d48, which comprises the gene bytA, encoding the pentapeptide MNYLH, bytO, encoding a cytochrome P450 (CYP450)-dependent enzyme and bytZ, which encodes an S-adenosyl-methionine-(SAM)-dependent methyltransferase.
