Figure 5.

Sarpogrelate suppressed TAC-induced phosphorylation of ERK and GATA4. (a,b) WCL from mouse heart was subjected to Western blotting to assess the levels of phosphorylated ERK1/2 and total ERK. Representative Western blotting images are shown in (a) and quantified levels of phosphorylated and total ERK1/2 in (b). (c,d) NE fractions from mouse heart were subjected to Western blotting to assess phosphorylated GATA4 and total GATA4. Representative images of Western blotting are shown in (c) and quantified phosphorylated and total GATA4 levels in (d). All data are presented as the mean ± SEM of four individual experiments.