T2DM |
Type 2 diabetes mellitus |
CVD |
Cardiovascular disease |
apoB-100 |
Apolipoprotein B-100 |
HDL |
High-density lipoprotein |
LDL |
Low-density lipoprotein |
MM-LDL |
Minimally oxidized LDL |
Ox-LDL |
Oxidized LDL |
VLDL |
Very-low-density lipoprotein |
LPL |
Lipoprotein lipase |
CETP |
Cholesteryl ester transfer protein |
TG |
Triglycerides |
CE |
Cholesteryl esters |
FC |
Free cholesterol |
sdLDL |
Small and dense LDL |
LDLR |
LDL receptors |
IDL |
Intermediate-density lipoprotein |
apoA-I |
Apolipoprotein A-I |
HDL-C |
HDL-cholesterol |
DM |
Diabetes mellitus |
IMT |
Intima-media thickness layer |
LDL-C |
LDL-cholesterol |
NEFA |
Non-esterified fatty acids |
PI-3K |
Phosphatidylinositol-3 kinase |
MAPK |
Mitogen-activated protein kinase |
MTP |
Microsomal TG-transfer protein |
SRs |
Scavenger receptors |
SR-A1 |
Class A1 scavenger receptor |
LOX-1 |
Lectin-like oxidized LDL receptor-1 |
SREC |
Scavenger receptor expressed by endothelial cell-I |
SR-PSOX |
Scavenger receptor for phosphatidylserine and oxidized lipoprotein |
AKT |
Protein kinase B |
JNK |
Janus kinase |
NF-κB |
Factor nuclear kappa B |
β2ΓΠΙ |
Beta2-glycoprotein I |
CRP |
C-reactive protein |
TNF-α |
Tumor necrosis factor-α |
PDGF |
Platelet-derived growth factor |
PPAR-γ |
Peroxisome proliferator-activated receptor γ |
9-HODE |
9-hydroxyoctadecadienoic acid |
13-HODE |
13-hydroxyoctadecadienoic acid |
PUFA |
Polyunsaturated fatty acids |
HbAIC |
Glycated hemoglobin |
MPO |
Myeloperoxidase |
NADPH |
Nicotinamide adenine dinucleotide phosphate |
HOCl |
Hypochlorous acid |
AGEs |
Advanced glycation end products |
O2−
|
Superoxide anion |
ROS |
Reactive oxygen species |
NO |
Nitric oxide |
eNOS |
Endothelial NO synthase |
Lp-PLA2 |
Lipoprotein-associated phospholipase A2 |
1ΔgO2
|
Singlet oxygen |
O3
|
Ozone |
PKC |
Protein kinase C |
ALEs |
Advanced lipoxidation end-products |
CER |
Ceramides |
IRS |
Insulin receptor substrates |
MMP |
Metalloproteinases |
THP-1 |
Monocytic cell line |
CREM |
cAMP-responsive element modulator |
ICER |
Inducible cAMP early repressor |
ER |
Endoplasmic reticulum |
PEDF |
Pigment epithelium-derived factor |
iNOS |
Inducible NO synthase |
MACEs |
Major adverse cardiovascular events |
NPC1L1 |
Niemann–Pick C1-like 1 protein |
SGLT2i |
Sodium-glucose cotransporter 2 inhibitor |
GLP-1 |
Glucagon-like peptide- |
DPP-4 |
Dipeptidyl peptidase-4 |
SLC2A4 |
Insulin-sensitive solute carrier family 2, member 4 |
HMGCR |
3-hydroxy-3-methylglutaryl-coenzyme A reductase |
FH |
Familial hypercholesterolemia |