Table 3.
Echocardiographic, laboratory and clinical characteristics of COVID-19 patients at six months after initial hospital admission.
| Myocardial Injury (n = 43) |
No Myocardial Injury (n = 43) |
p-Value | |
|---|---|---|---|
| Echocardiographic characteristics | |||
| Interventricular septum wall thickness, mm * | 10.0 (9.00–12.0) | 9.00 (8.00–10.5) | 0.002 |
| Posterior wall thickness, mm * | 10.0 (9.00–11.0) | 8.00 (7.00–10.0) | 0.002 |
| LV telediastolic diameter, mm * | 50.0 (45.0–55.5) | 49.0 (45.0–53.0) | 0.659 |
| LV telesistolic diameter, mm * | 30.0 (26.5–34.5) | 30.0 (27.0–32.5) | 0.274 |
| LV end diastolic volume, mL * | 91.0 (81.0–108) | 85.0 (75.5–101) | 0.111 |
| LV end systolic volume, mL * | 33.0 (26.0–46.0) | 32.0 (25.0–41.5) | 0.380 |
| LV ejection fraction (Simpson’s biplane), % * | 63.0 (60.0–67.5) | 63.0 (58.0–67.8) | 0.833 |
| TAPSE, mm * | 23.0 (21.0–25.0) | 23.0 (20.2–24.8) | 0.951 |
| E/E’ratio * | 8.00 (6.2–9.50) | 8.00 (6.00–9.05) | 0.303 |
| PAP, mmHg * | 34.0 (27.5–37.8) | 29.0 (27.0–31.0) | 0.021 |
| Laboratory characteristics | |||
| Urea, mg/dL * | 43.0 (35.0–52.0) | 38.0 (32.5–44.6) | 0.028 |
| Creatinine, mg/dL * | 1.01 (0.88–1.17) | 0.91 (0.81–1.04) | 0.041 |
| Glomerular filtrate rate, mL/min/1.73 m2 ** | 71.5 (24.3) | 82.9 (20.4) | 0.021 |
| C-Reactive Protein, mg/dL * | 0.18 (0.10–0.37) | 0.13 (0.08–0.24) | 0.236 |
| NT-proBNP, pg/L * | 119 (73.9–234) | 71.3 (32.9–120) | 0.001 |
| Haemoglobin, g/dL ** | 13.2 (1.40) | 14.1 (1.29) | 0.002 |
| Leukocytes/µL×103 * | 7020 (6170–7790) | 6600 (5395–7670) | 0.260 |
| Lymphocytes/µL×103 * | 1910 (1235–2205) | 2080 (1710–2555) | 0.062 |
| D-Dimer, ng/mL * | 295 (205–388) | 230 (190–375) | 0.137 |
| Clinical characteristics | |||
| Chest pain | 4.65% | 2.33% | 1.00 |
| Palpitations | 4.65% | 0.00% | 0.494 |
| NYHA functional class I-II NYHA functional class III-IV |
93.0% 7.00% |
97.7% 2.30% |
0.407 |
| Pulse oximetry * | 98.0 (97.0–99.0) | 97.0 (96.5–98.0) | 0.098 |
| Systolic blood pressure ** | 141 (17.0) | 136 (18.6) | 0.194 |
| Diastolic blood pressure ** | 77.3 (11.7) | 77.9 (13.2) | 0.826 |
* Median (Inter-quartile range) ** Mean (standard deviation); LV, left ventricular; TAPSE, Tricuspid Annular Plane Systolic Excursion; PAP, pulmonary artery pressure; NT-proBNP, N-terminal prohormone of brain natriuretic peptide; NYHA, New York Heart Association.