Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Duality of PDKs in PCa. (A) The high expression of PDKs regulated by CD44, PPARr, hypoxia, and KDM4A/B promotes PCa proliferation, migration in cell lines and xenograft models. (B) On the other hand, the low expression of PDK4 regulated by STAT3 leads to early recurrence and PCa lipogenesis by increasing PDH activity in clinical patient samples and transgenic PtenKO mouse model.
