Table 5.

% Inhibition values of the synthesized compounds 3a and 4a–f over EGFR kinase at a single dose concentration of 10 µM.

Cpd	Average % Enzyme Inhibition (Relative to DMSO Controls) at 10 µM
3a	−13.16 ± 4.31
4a	0.56 ± 4.32
4b	25.25 ± 1.25
4c	46.78 ± 0.54
4d	65.76 ± 0.98
4e	63.28 ± 0.21
4f	4.57 ± 2.16
Staurosporine	-