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. 2021 Dec 20;22(24):13678. doi: 10.3390/ijms222413678

Figure 4.

Figure 4

Myocardial inflammatory cell infiltration. Effects of C21 and Ang 1-7 administration on myocardial inflammatory cell infiltration in Ang II treated rats for 1 and 4 weeks. (a). Immunohistochemical identification of interstitial monocyte/macrophage infiltration (brown reaction) in control (A,F), Ang II (B,G), Ang II + C21 (C,H), Ang II + Ang 1-7 (D,I) and Ang II + Los (E,J) treated rats (×20 magnification), at 1 and 4 weeks of treatment. (b). Quantification of staining of myocardial monocyte/macrophage inflammatory cells in the different groups of rats. Data are means ± SEM. *: p  <  0.05. §: p  <  0.01. (c). Immunohistochemical identification of interstitial T-lymphocyte infiltration (brown reaction) in control (K,P), Ang II (L,Q), Ang II + C21 (M,R), Ang II + Ang 1-7 (N,S) and Ang II + Los (O,T) treated rats (×20 magnification), at 1 and 4 weeks of treatment. (d). Quantification of staining of myocardial T-lymphocyte inflammatory cells in the different groups of rats. Data are means ± SEM.